Thymosin Alpha-1

Thymosin alpha 1 is a 28-amino-acid peptide released from prothymosin alpha, originally isolated from thymus tissue. It signals mainly through Toll-like receptors on dendritic cells and monocytes, which places it upstream of T-cell maturation rather than acting on T-cells directly — the distinction that most of the mechanistic literature is concerned with.

Research context

• Toll-like receptor signalling in dendritic cells
• T-cell maturation and differentiation
• Cytokine production and immune balance
• Innate immune response in challenge models

Allow the vial to reach room temperature before opening. Reconstitute with bacteriostatic water introduced slowly against the vial wall — do not inject directly onto the lyophilized cake and do not shake.

• Store lyophilized at −20 °C, protected from light.
• Store reconstituted solution at 2–8 °C and use within the study window.
• Avoid repeated freeze–thaw cycles.
• Handle under standard laboratory practice with appropriate PPE.

Orders are dispatched same-day when placed before 14:00 local time. Compounds ship lyophilized and are shelf-stable in transit; packaging is discreet and tamper-evident with tracking on every order.

A lot-specific Certificate of Analysis is issued for every batch and is available from the lab results library.