KPV

KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone. The parent hormone does two things: it drives pigmentation through MC1R, and it damps inflammation. This fragment retains the second without the first, which makes it a way to study the anti-inflammatory arm in isolation. Its small size also lets it enter cells directly rather than signalling only from the surface.

Research context

• NF-kB signalling and pro-inflammatory cytokine output
• Intestinal epithelial inflammation models
• Mast cell activation studies
• Intracellular transport of short peptides

Allow the vial to reach room temperature before opening. Reconstitute with bacteriostatic water introduced slowly against the vial wall — do not inject directly onto the lyophilized cake and do not shake.

• Store lyophilized at −20 °C, protected from light.
• Store reconstituted solution at 2–8 °C and use within the study window.
• Avoid repeated freeze–thaw cycles.
• Handle under standard laboratory practice with appropriate PPE.

Orders are dispatched same-day when placed before 14:00 local time. Compounds ship lyophilized and are shelf-stable in transit; packaging is discreet and tamper-evident with tracking on every order.

A lot-specific Certificate of Analysis is issued for every batch and is available from the lab results library.